侯红件

一、个人简介

侯红件，女，汉族，1990年10月，河南永城人，博士，讲师。

二、教育背景及工作经历

2020.07 -至今，商丘师范学院，生物与食品学院，讲师；

2017.09-2020.06，徐州医科大学，生理学，博士；

2018.11 – 2019.05，英国帝国理工学院Imperial College London,心血管药理学，联合培养博士；

2016.07-2017.06，苏州大学，科研助理；

2013.09-2016.06，徐州医科大学，生理学，硕士；

2009.09 – 2013.06,天津商业大学，生物技术与食品科学学院，制药工程专业，学士。

三、教学情况

主要讲授课程：《果蔬加工技术》、《果蔬加工技术实验》、《功能性食品实验》、《食品添加剂实验》、《中医中药学实验》等课程。

四、承担的科研项目

1.商丘师范学院博士科研启动项目，No.7001/700216，《雌激素调节巨噬细胞抗应激性心肌损伤的作用机制》，2020.10-2023.9，15万，在研，主持；

2.江苏省科研创新计划项目，项目编号KYCX18_2167，《雌激素经β2AR-G蛋白调节巨噬细胞抗应激性心肌损伤的研究》，2018/05-2020/04，1.5万，结题，主持；

3.国家自然基金-国际(地区)合作与交流项目，8141101059，《基于hiPSC-CM的雌激素调节βAR信号通路抗应激性心肌病的研究》，2015/01/01—2018/12/31，260万元，结题，参与；

4.国家自然科学基金面上项目，81370329，《雌激素通过调制β肾上腺素受体和G蛋白信号通路发挥抗应激性心肌病的研究》，2014/01-2017/12，75万元，结题，参与；

五、论文和专著

1.Hongjian Hou,Gabriel Komla Adzika, QiWu, et al. Estrogen attenuates chronic stress-induced cardiomyopathy by adaptively regulating macrophage polarizations via β2-adrenergic receptor modulation. Frontiers in Cell and Development Biology. 2021, 9: 737003.

2.Pei Shao,Hongjian Hou, Wenlong Wang, et al. Geochemistry and mineralogy of fly ash from the high-alumina coal, Datong Coalfield, Shanxi, China.Ore geology review.2023,158:105476.

3.Pei Shao,Hongjian Hou, Wenlong Wang, et al. Distribution and enrichment of Al-Li-Ga-REEs in the High-Alumina coal of the Datong Coalfield, Shanxi Province, China.Ore geology review.2022,140:104597.

4.Gabriel Komla Adzika,Hongjian Hou, Adekunle AO, et al. Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses. Frontiers in Cell and Developmental Biology. 2021, 9: 719351.

5.Gabriel Komla Adzika,Hongjian Hou, Adekunle AO, et al. Isoproterenol-induced cardiomyopathy recovery intervention: amlexanox and forskolin enhances the resolution of catecholamine stress-induced maladaptive myocardial remodeling. Frontiers in Cardiovascular Medicine. 2021, 8: 719805.

6.Hongjian Hou, Zhiwei Zhao, Machuki Jeremiah Ong’achwa, et al. Estrogen deficiency compromised the β2AR-Gs/Gi coupling: implications for arrhythmia and cardiac injury. Pflügers Archiv - European journal of Physiology. 2018, 470(3): 559-570. ²

7.Jingmin Chong,HongJian Hou, Yan Zhang, et al. Stress Cardiomyopathy was Prone to Occur in Patients with Chronic Diseases: Maybe a Good Thing. Cardiovascular Pharmacology: Open Access. 2016. 5(1): 1-5.²

8.Gabriel Komla Adzika, Jeremiah Ong’achwa Machuki, Wenkang Shang,Hongjian Hou, et al. Pathological cardiac hypertrophy: the synergy of adenylyl cyclases inhibition in cardiac and immune cells during chronic catecholamine stress. Journal of Molecular Medicine. 2019. 97(7): 897-907.

9.Xiancun Cao, Chunle Zhou, Jingmin Chong, Lu Fu, Lin Zhang, Di Sun,HongjianHou, et al. Estrogen resisted stress-induced cardiomyopathy through increasing the activity of β2AR-Gαs signal pathway in female rats. International Journal of Cardiology. 2015. 187: 377-386.

10.桑黎黎,周春乐,付璐,种静敏,张岩,侯红件,孙红,高兴亚.肾上腺素致大鼠应激性心肌损伤性别差异研究倡[J].徐州医学院学报. 2015(2): 101-104.

11.王雪青，宋文军，李长文，白晓丽，侯红件，何长江.葛根素通过调控炎性因子水平降低营养性肥胖大鼠的体质量[J].食品科学, 2012, 33(21): 298-303.