一、个人基本情况
李俊敏，女，1988.10，河南省商丘市，中共党员，2022年毕业于华南理工大学医药生物学专业，生物与食品学院生物工程专业教师，讲师，工科实训中心103室办公。主持国家自然科学基金、河南省科技厅、河南省教育厅项目各1项；在Analytica Chimica Acta等国际期刊发表论文11篇，申请实用新型发明专利3项。
二、教育经历和工作经历
教育经历
(1) 2015-09至2022-06,华南理工大学,医药生物学,博士
(2) 2012-09至2015-07,华南理工大学,生物化学与分子生物学,硕士
(3) 2007-09至2011-07,南阳师范学院,生物科学,学士
工作经历
2023-01至今,商丘师范学院,生物与食品学院,讲师
三、主讲课程
主讲《遗传学》，《生物制药工艺学》，《生命科学研究进展》等课程。
四、承担项目
1.国家自然科学基金，LP-scFv增强HER2单链抗体scFv内吞作用及其抗肿瘤活性的分子机制研究（82503632），2026.01.01-2028.12.31，在研，主持
2.河南省自然科学基金项目，LP-scFv促进HER2单链抗体scFv抗癌活性机制研究（242300421533），2024.01-2025.12，在研，主持
3.河南省教育厅,河南省高等学校重点科研项目, LP-scFv促进HER2单链抗体scFv抗癌活性机制及其应用研究（24A310009）, 2024.01-2025.12，在研，主持
五、发表论文
1.Junmin Li; Xue Li; Ruixin Fu; Yakun Fang; Chunmei Zhang; Bingbing Ma; Yanan Ding; Chuanxin Shi; Qingfeng Zhou; Recent Research Advances in HER2-Positive Breast Cancer Concerning Targeted Therapy Drugs, Molecules, 2025, 30(14): 3026.
2.Junmin Li; Yanting Zhou; Zhuowei Su; Xue Li; Lei Zhang; Shan Li; A Cell Penetrating Peptide Improves Anti-HER2 ScFv Internalization and Antitumor Activity against HER2-Positive Breast Cancer in Vitro and in Vivo, Molecules, 2024, 29(06): 7205.
3.Junmin Li; Xuejiao Hu; Xiaoming Wang; Jianing Yang; Lei Zhang; Qianyun Deng; Xiqin Zhan; Zixia Wang; Tieying Hou; Shan Li; A Novel One-Pot Rapid Diagnostic Technology for COVID-19, Analytica Chimica Acta, 2021, 1154: 338310.
4. XuejiaoHu#; Qianyun Deng#;Junmin Li#; Jierong Chen; Zixia Wang; Xiqin Zhang; Zhixin Fang; Haijian Li; Yunhu Zhao; Pan Yu; Wenmin Li; Xiaoming Wang; Shan Li; Lei Zhang; Tieying Hou; Development and Clinical Application of a Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for SARS-CoV-2 Infection, mSphere, 2020.08, 5(4): e00808-20.
5. Weiguo Wang;Junmin Li; Changzhi Dong; Yafang Li; Qiuye Kou; Jinwu Yan; Lei Zhang; Ultrasensitive ELISA for the detection of hCG based on assembled gold nanoparticles induced by functional polyamidoamine dendrimers, AnalyticaChimica Acta, 2018, 1042: 116-124.
6. Ruixin Fu; Mengyuan Zhu; Yanrong Zhang;Junmin Liand Haichao Feng; Harnessing the Rhizosphere Microbiome for Selenium Biofortification in Plants: Mechanisms, Applications and Future Perspectives. Microorganisms. 2025 May 28;13(6):1234.
7. Di Meng; Hongjian Hou; Jinbin Liu; Dandan Deng;Junmin Li; Kai Yang; Yakun Fang; Xiaoqin Zhu; Dongli Pei; A Priestia megaterium MF3 with high-efficiency zearalenone degradation: functional genomic insights and mechanistic exploration. Front Microbiol. 2025 Jul 1;16:1630165.
8. Ting Tan, Qianqian Cao, Ming-Hui Duan,Junmin Li, Yafeng Xie, Min Tan, Xiwu Yin, Jikai Wang, Weiguo Wang. Atomic-shell engineering in manganese-doped palladium@iridium nanozymes: d-Band optimization for enhanced peroxidase-like activity in ultrasensitive lateral flow immunoassays. Chemical Engineering Journal 2025, 524 , 169492.
9.Chuanxin Shi, Qingyan Zhu, Zhuangzhuang Lu, Yongqi Yang, Yanan Ding,Junmin Li, Chunmei Zhang, Li Xi, Xiaofang He, Zhiqiang Li, Jincheng Han, Guangli Yang, Yan Guo, Bingbing Ma. Predictive models of digestible and metabolizable energy of wheat in growing pigs. Front. Nutr.2025，12:1662909.
10. Yanan Ding, Ali Liu, Bingbing Ma, Huiqun Zhang, Chunmei Zhang,Junmin Li, Jincheng Han, Chuanxin Shi. Perinatal Antibiotic Timing Impairs Maternal IgG Transfer via FcRn and Shapes the Neonatal Gut Microbiome in Mice. Microorganisms, 2026, 14(2): 276.
11.李雪;李俊敏;张雷;李杉;细胞穿膜肽M918偶联抗体的表达纯化及其内吞效率研究,生物技术通报, 2021, 37(12): 198-204. (中文核心)
六、授权专利
1.李俊敏;施传信;马冰冰;卢壮壮;韩进诚;张春梅;朱庆妍;谢汶彤;周庆峰;用于鱼粉猪源性成分检测的引物组、试剂盒及其应用, 2024-10-16,中国, CN202411446069.7
2.施传信;马冰冰;周庆峰;李俊敏;魏文洁;梁欣萌;胡浩然;王怡博;胡艺蝶;张世华;王艺诗;张明慧;一种鱼粉质量检测引物组、试剂盒及应用, 2024-07-25,中国, CN202411006705.4
3.张雷;李杉;李俊敏;一 种HER2融合单链抗体、制备方法与应用, 2022-03-25,中国, ZL201710683659.5
